ST In-Check lab-on-chip is the market’s first silicon device that provides
integrated genetic analysis at a fraction of the time, cost, and complexity
of conventional diagnostic systems. The micro-electro-mechanical solution
in a disposable cartridge amplifies tiny DNA samples by precisely controlled
heating and cooling and runs biological protocols that evaluate the
analyzed substance.
Silicon’s low thermal capacity and the minute volumes of tested
samples reduce reaction times to less than 30% of standard macroscopic
equipment. Fast temperature cycling enables amplification of complex
biological materials in 20-30 minutes without compromising accuracy
and reliability.
An embedded microcontroller actuates, monitors, and adjusts the parameters
of the reaction. A simple graphical user interface installed in a standard
PC allows easy customization and control of temperatures, reaction times,
and spot sizes in the most complex diagnostic applications. Encapsulated
in a single, self-contained unit, ST’s biochip significantly reduces
the risks of cross-contamination inherent in conventional analysis methods.
ST’s In-Check lab-on-chip opens up new possibilities for instant
and affordable analysis of complex biological substances at the point
of need. Fast time-to-answer, portability, and ease-of-use makes In-Check
particularly suitable for operation in real-world conditions, spanning
a wide array of health- and life-saving applications, including detection
of infectious and genetic diseases; testing food and water supplies
for dangerous microorganisms; veterinary diagnostics; and drug development.
Partners that develop their genomic applications on the In-Check platform
have access to an extensive network of manufacturing plants across the
world. Dedicated MEMS and Lab-on-Chip fabs work with high-volume plants
to offer the best combination of R&D intensive efforts and low-cost
manufacturing. A seasoned team of engineers, scientists, managers and
operations personnel with over 10 years experience in microfluidic devices
is contributing to the success of this innovative platform.
Updated June 2006
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